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DOCK (Dedicator of cytokinesis) is a family of related proteins involved in intracellular signalling networks. Studies to date suggest that this family act as guanine nucleotide exchange factors for small G proteins of the Rho family, such as Rac and Cdc42. DOCK family proteins are categorised into four subfamilies based on their sequence homology: *DOCK-A subfamily * *Dock180 (also known as Dock1) * *Dock2 * *Dock5 *DOCK-B subfamily * *Dock3 (also known as MOCA and PBP) * *Dock4 *DOCK-C subfamily (also known as Zir subfamily) * *Dock6 (also known as Zir1) * *Dock7 (also known as Zir2) * *Dock8 (also known as Zir3) *DOCK-D subfamily (also known as Zizimin subfamily) * *Dock9 (also known as Zizimin1) * *Dock10 (also known as Zizimin3) * *Dock11 (also known as Zizimin2) ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「DOCK (protein)」の詳細全文を読む スポンサード リンク
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